Symptoms of DVT are pain or tenderness in one leg only, skin discoloration, and joint pain. It can be accompanied by fever, a sudden, unexplained cough, or joint pain.DVT usually affects veins in the lower leg and thigh. It occurs when a blood clot forms in the larger veins; this clot (or thrombus) may interfere with circulation or break off and embolize. The embolus moves though the blood stream and can lodge in any area, causing severe damage to the organ where it settles. The most common is a pulmonary embolism, when the embolus lodges itself in a patient's lung. DVT occurs in approximately 2 out of 1,000 people, most of who are over age 60.