Vioxx: An Alternative for Those with Osteoarthritis

Vioxx has become one of the fastest-selling drugs in the world. The FDA approved Vioxx in May of 1999 for the treatment of osteoarthritis (OA), menstrual pain, and the management of acute pain in adults. Drug sales have soared since last spring, and reports indicate that more than 6 million Americans are currently taking Vioxx.

Osteoarthritis (OA) is the most common form of arthritis. According to the American Medical Association it affects more than 16 million Americans. It is a degenerative disease associated with wear and tear and it is mainly found in the elderly. People suffering with OA often have pain and a limited range of motion in one or both knees. This pain and inflammation causes significant discomfort and because there is no cure for arthritis, patients rely on medications such as aspirin, ibuprofen, naproxen, or other non-steroidal anti-inflammatory drugs (NSAIDS) to provide relief. Although NSAIDS may improve comfort levels they may also produce damaging effects such as stomach upset, gastrointestinal problems, bleeding and ulcers.

Vioxx is a new non-steroidal anti-inflammatory drug; it is the second drug approved in a class of drugs referred to as Cox-2 inhibitors. The Cox-2 inhibitors work in a similar manner to the traditional NSAIDS in blocking pain and inflammation, but studies show that they are less likely to produce stomach upset, ulcers or bleeding. Although the development of Cox-2 inhibitor drugs, such as Vioxx, is an exciting alternative for people suffering from OA, and other forms of acute pain, doctors state that it is not a miracle drug; it may help patients manage the disease but it will not change the course of the disease.